Moderna vaccine as a third dose produced especially strong responses
People with undetectable HIV who received SARS-CoV-2 vaccines didn’t experience faster antibody declines than people without HIV after two vaccine doses and had equivalent or better antibody responses compared to a control group after a third dose, especially those who received the Moderna vaccine as their third dose, Canadian researchers report in a pre-print article released before peer review.
The study found no evidence of weaker virus neutralisation nor any evidence of weaker vaccine responses in people with a history of a low CD4 cell count. Most people in this study received the Pfizer or Moderna mRNA vaccines but there was some evidence that the Oxford-AstraZeneca vaccine was associated with weaker responses after the first two doses.