Laboratory

Long-term care residents show weaker immune response to first dose of vaccine

A new study recommends giving elderly people their second dose on schedule. As B.C. prepares to relax visitation restrictions at long-term care facilities on April 1, new research shows that a single dose of the Pfizer vaccine produces a much weaker antibody response in long-term care residents than it does in younger, healthy adults. That

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Weak antibody response to first vaccine dose may leave older adults vulnerable

The findings raise questions about the optimal timing of the second dose of the vaccine for older adults. “Results from this study in long-term care facilities in Vancouver reveal that individuals of advanced age, following the first dose of a two-dose vaccination regimen, are less able to generate as strong an antibody response, both in

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BC-CfE research on coronavirus evolution helps in vaccine design and deepens understanding of viral mutations

The BC-CfE continues to lead the way in COVID-19 research, with the latest published research on the topic coming from the Centre’s Molecular Epidemiology and Evolutionary Genetics Group.

The paper, which features contributions from almost all members of the group, focuses on evolutionary patterns among coronaviruses that have jumped from animal hosts into humans and is titled “Variable routes to genomic and host adaptation among coronaviruses“.

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$1.2M grant aims to investigate the immune response of LTC residents to COVID-19 vaccines

FHS professors Mark Brockman and Zabrina Brumme are co-leading a study with Dr. Marc Romney, the Medical Lead for Microbiology and Virology at Providence Health Care, to examine the strength and durability of immune responses in residents and staff of long-term care facilities following COVID-19 vaccination. Their study partners include UBC and the BC Centre

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BC-CfE researchers collaborate to determine impact of COVID-19 vaccines in residents of long-term care facilities in BC

BC-CfE researchers are working alongside colleagues from the University of British Columbia, Providence Health Care, and Simon Fraser University to investigate how elderly peoples’ immune systems respond to COVID-19 vaccines. The researchers will also assess the viral, immunological and social factors that have contributed to COVID-19 outbreaks in long-term care facilities in order to better understand why and how the disease has been fatal to so many residents.

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COVID-19: As care home residents get second vaccine doses, study aims to track their antibody levels

A virologist said it may be months before restrictions for visitors are lifted, and freedoms and procedures at seniors’ homes may never return to pre-COVID times. Residents of seven B.C. seniors’ homes, including one with one of the deadliest COVID-19 outbreaks, have been or soon will be fully vaccinated, but a virologist studying how well

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