Long-term care residents show weaker immune response to first dose of vaccine

A new study recommends giving elderly people their second dose on schedule.

As B.C. prepares to relax visitation restrictions at long-term care facilities on April 1, new research shows that a single dose of the Pfizer vaccine produces a much weaker antibody response in long-term care residents than it does in younger, healthy adults.

That could have serious consequences for elderly people who live in the general community and may have to wait up to four months for their second dose.

“There are many people who are frail and elderly living in the community, and there is no reason to believe their immune systems are any different than people in long-term care,” said the study’s lead author, Dr. Marc Romney, who is a professor at the University of B.C. and a medical leader in virology at St. Paul’s Hospital.

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During the Canada Post strike announced September 25, 2025, the following measures will be undertaken to minimize service disruption to BC-CfE clients and providers.

  • The BC-CfE Laboratory has transitioned to private courier for delivery of outgoing reports and documents. Results required urgently can be faxed upon request. (Lab Contact Information: Phone 604-806-8775; FAX 604-806-9463)
  • The BC-CfE Drug Treatment Program (DTP) will fax outgoing forms and documents to the provider’s office. (DTP Contact Information: Phone 604-806-8515; FAX 604-806-9044)
  • St. Paul’s Hospital Ambulatory Pharmacy has transitioned to private courier for delivery of medications. We recommend requesting medication at least 2 weeks in advance in case of delivery delays, particularly to rural/remote parts of BC. (Contact Information: Phone 1-800-547-3622; FAX 604-806-8675)

During the Canada Post strike, we recommend that documents be faxed or couriered to our sites, versus utilization of regular mail service

The BC-CfE Laboratory is streamlining reporting processes for certain tests in order to simplify distribution and record-keeping, and to ensure completeness of results. Beginning September 2, 2025, results for the ‘Resistance Analysis of HIV-1 Protease and Reverse Transcriptase’ (Protease-RT) and ‘HIV-1 Integrase Resistance Genotype’ tests will be combined into a single ‘HIV-1 Resistance Genotype Report’.
For more details and example reports, please click on the button below

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