HIV Post-Exposure Prophylaxis (PEP) Guidelines

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For information on how to obtain medication for prevention of HIV infection following a high risk occupational or non-occupational exposure, please call the St Paul’s Hospital Ambulatory Pharmacy 1-888-511-6222

 

  • This guideline is intended to guide health care providers caring for persons who have experienced significant exposure to blood and/or body fluids in the work place or community setting. The risk of HIV acquisition from a given exposure depends on the likelihood the source has transmissible HIV infection, and the biological risk of HIV transmission based on the exposure that has occurred.
  • This guideline is designed to deal specifically with exposures to Human Immunodeficiency Virus (HIV) and is not applicable to other exposures such as viral hepatitis.
  • This guideline provides a framework for a program of expert advice and prompt antiretroviral post-exposure prophylaxis (PEP) for potential exposures to HIV.
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During the Canada Post strike announced September 25, 2025, the following measures will be undertaken to minimize service disruption to BC-CfE clients and providers.

  • The BC-CfE Laboratory has transitioned to private courier for delivery of outgoing reports and documents. Results required urgently can be faxed upon request. (Lab Contact Information: Phone 604-806-8775; FAX 604-806-9463)
  • The BC-CfE Drug Treatment Program (DTP) will fax outgoing forms and documents to the provider’s office. (DTP Contact Information: Phone 604-806-8515; FAX 604-806-9044)
  • St. Paul’s Hospital Ambulatory Pharmacy has transitioned to private courier for delivery of medications. We recommend requesting medication at least 2 weeks in advance in case of delivery delays, particularly to rural/remote parts of BC. (Contact Information: Phone 1-800-547-3622; FAX 604-806-8675)

During the Canada Post strike, we recommend that documents be faxed or couriered to our sites, versus utilization of regular mail service

The BC-CfE Laboratory is streamlining reporting processes for certain tests in order to simplify distribution and record-keeping, and to ensure completeness of results. Beginning September 2, 2025, results for the ‘Resistance Analysis of HIV-1 Protease and Reverse Transcriptase’ (Protease-RT) and ‘HIV-1 Integrase Resistance Genotype’ tests will be combined into a single ‘HIV-1 Resistance Genotype Report’.
For more details and example reports, please click on the button below

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