Programmatic implications of acute and early HIV infection

2015 | J Infect Dis

Topic(s): Treatment as Prevention® |

Abstract:

HIV infection includes acute, early, chronic, and late stages. Acute HIV infection lasts approximately three weeks and early HIV infection lasts approximately seven weeks. Many testing and blood screening algorithms detect HIV antibodies about three weeks after HIV infection. Incidence estimates are based on modelling, cohorts, surveillance, and/or assays. Viral load is the key modifiable risk factor for HIV transmission and peaks during acute and early HIV infection. Data characterising the impact of acute and early HIV infection on the spread of the HIV epidemic are variable. Time trends of HIV prevalence collected from concentrated and generalised epidemics suggest that acute and early HIV infection has a limited role in population HIV transmission. Collectively, these data suggest that acute and early HIV infection does not require different programmatic approaches to manage the epidemic. On-going research will continue to inform the implications of acute and early HIV infection for HIV programmes.

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Suthar AB

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© Copyright BC Centre for Excellence in HIV/AIDS
St. Paul's Hospital 608–1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
Tel: 604-806-8477 | Fax: 604-806-9044
General inquiries: info@bccfe.ca
Media inquiries: communications@bccfe.ca
(Please do not use any of these email addresses to send personal information or book an appointment. To book appointments or contact the H2H clinic, please call 604-416-1517 or fax: 604-564-4893. Do not send your or your client's personal information via email.)

© Copyright BC Centre for Excellence in HIV/AIDS
St. Paul's Hospital 608–1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
Tel: 604-806-8477 | Fax: 604-806-9044
General inquiries: info@bccfe.ca
Media inquiries: communications@bccfe.ca
(Please do not use any of these email addresses to send personal information or book an appointment. To book appointments or contact the H2H clinic, please call 604-416-1517 or fax: 604-564-4893. Do not send your or your client's personal information via email.)

Our work serves clients and communities across British Columbia on lands and waters cared for and nurtured by the many distinct First Nations across the province. The BC-CfE humbly and gratefully acknowledge the stewards of these lands, particularly the xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh (Squamish), and səl̓ílwətaʔ (Tsleil-Waututh) on whose unceded, traditional and ancestral territories our offices are located.