Fauci: Follow the Science to End the HIV/AIDS Epidemic

published on October 24, 2016 by Marcia Frellick, in medscape

GLASGOW, United Kingdom — The possibility of controlling HIV without eradicating the virus is a hot new area of research, Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases, said here during the opening session of HIV Drug Therapy 2016.

In fact, he presented results from a study of an antibody against the cell receptor alpha4beta7 integrin, the homing receptor for CD4-positive T-cells, earlier this month at the HIV Research for Prevention meeting in Chicago.

In that study, monkeys infected with the simian version of HIV were treated with antiretroviral therapy. They were then given the antibody and treatment was discontinued.

Almost 2 years later, the monkeys "have replication-competent virus but they have no viremia," Dr Fauci reported. "I have no idea what the mechanism of that is, but that's something we're really pursuing."

The National Institutes of Health recently started an exploratory open-label study of vedolizumab — the commercially available version of that antibody — in human subjects.

"We entered the first patient in August and, hopefully, by the end of 2017 or early 2018, we will have some answers," said Dr Fauci.

View the full article >>

Tags:

Treatment as Prevention®

Our work serves clients and communities across British Columbia on lands and waters cared for and nurtured by the many distinct First Nations across the province. The BC-CfE humbly and gratefully acknowledge the stewards of these lands, particularly the xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh (Squamish), and səl̓ílwətaʔ (Tsleil-Waututh) on whose unceded, traditional and ancestral territories our offices are located.

© Copyright BC Centre for Excellence in HIV/AIDS
St. Paul's Hospital 608–1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
Tel: 604-806-8477 | Fax: 604-806-9044
General inquiries: info@bccfe.ca
Media inquiries: communications@bccfe.ca
(Please do not use any of these email addresses to send personal information or book an appointment. To book appointments or contact the H2H clinic, please call 604-416-1517 or fax: 604-564-4893. Do not send your or your client's personal information via email.)

© Copyright BC Centre for Excellence in HIV/AIDS
St. Paul's Hospital 608–1081 Burrard Street, Vancouver, BC, Canada V6Z 1Y6
Tel: 604-806-8477 | Fax: 604-806-9044
General inquiries: info@bccfe.ca
Media inquiries: communications@bccfe.ca
(Please do not use any of these email addresses to send personal information or book an appointment. To book appointments or contact the H2H clinic, please call 604-416-1517 or fax: 604-564-4893. Do not send your or your client's personal information via email.)

Our work serves clients and communities across British Columbia on lands and waters cared for and nurtured by the many distinct First Nations across the province. The BC-CfE humbly and gratefully acknowledge the stewards of these lands, particularly the xʷməθkʷəy̓əm (Musqueam), Sḵwx̱wú7mesh (Squamish), and səl̓ílwətaʔ (Tsleil-Waututh) on whose unceded, traditional and ancestral territories our offices are located.